Thứ Hai, 13 tháng 1, 2014

Pemphigus Vulgaris

Pemphigus Vulgaris Pemphigus vulgaris is a type of skin rash causing blisters or bumps on the upper layer of the skin. It occurs in genitals or in your mouth causing irritation and discomfort. It can affect both men and women equally and largely seen in middle aged people or old aged. It is a chronic disease but an early diagnosis helps to manage the disease easily through medications.

Symptoms :

The lumps or blisters are formed on the skin which leaves pus like liquid discharge on the affected area. It starts as small lesions on the mouth which slowly get erupted and enters into the skin. Soft and delicate mucous membranes of the genitals are also affected by blisters. Normally these blisters are itching and painful making it difficult to use the organ.

There will be severe irritation, pain, and discomfort due to blisters or sores. These blisters spread rapidly to the neighboring parts of the skin causing more and more discomfort. Fever and chills are certainly present in many people due to this infection. Some people may also get joint pain during this period.

Pemphigus vulgaris occur on the mouth and on the mucous membranes of genitals. Once you have got red colored blisters you cannot eat or drink easily due to pain.

Pemphigus foliaceus affect the mucous membranes of the face, which slowly affects the scalp and spread over the chest and back portion causing painful blisters.

Causes :

The exact cause of this disease is not known, but it is believed to be autoimmune disorder. In this condition the body’s self immune system attacks and destroys the healthy cells of your skin causing blisters and sores. It mistakes the healthy cells for the presence of virus or bacteria and accordingly destroys it completely.

In rare cases, pemphigus vulgaris occur as adverse effect of certain medicines given for controlling blood pressure.

Complications :

If left unattended, this infectious disease can cause serious infection that spreads into the blood causing sepsis. It also gives the risk of spreading the infection to other organs of the body causing more complications.

Diagnoses :

Pemphigus cannot be diagnosed easily since the same symptoms are seen in several other diseases. Your doctor will collect your medical history and closely examine your mouth and skin. He may do a skin biopsy for collecting piece of skin tissue from the blister to get it tested on the lab. He may order for complete blood test for measuring the amount of antibodies.

Treatment :

Pemphigus vulgaris can be cured completely and it is easy to manage the symptoms if detected at early stages.

The doctor will analyze the health condition of the patient and accordingly gives treatment.

Medications of corticosteroids like prednisone are given orally for extended period of time. But you need to careful in not exceeding the recommended dosage since it can cause side effects. Some doctors would prescribe immunosuppressant like imuran, trexall or cellcept for boosting the immune system and preventing the immune system from destroying healthy tissues.

Biological therapies like rituximab are given for increasing the production of antibodies in the system to fight pemphigus. In case the infection is due to virus or bacteria antibiotics are given for controlling it.

The patient will be hospitalized if his/her health condition is not normal or if the infection has spread widely to various body parts and internal organs.

Intravenous fluids are administered for preventing fluid loss and balancing electrolytes in the body. If there is too much of ulcers and blisters on the mouth, intravenous feeding is recommended. Your doctor will give mouth lozenges to control pain arising from mouth sores.

Plasma from the blood cells is removed using cell separator device for destroying the antibodies that destroys your healthy cells.

Pictures of Pemphigus Vulgaris :

Images, Pics, Pictures and Photos of Pemphigus Vulgaris

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Home Care :

Avoid getting wounds in the body which increases the chance of spreading infection. Be careful not to get any injury or cracks on your skin so that it gives room for infectious virus entry.

You can apply talcum powder liberally to manage the pus or fluid like discharge oozing from your skin. Avoid foods that trigger infection and totally avoid acidic food stuff. You can apply lotions or creams on the blisters for minimizing the discomfort and pain.

You can consult your doctor about the intake of medications that may cause infection and reduce it or take alternate medicines.

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